Yes, we have done repeated patch testing, abrasion testing, ASTM validation, HETCAM studies, and completed a safety study ISO cytoxic report. Our formula has not resulted in adverse events and does not indicate a potential for dermal irritation or allergic contact sensitization. AllDay was given a 100% “non-irritating” classification. After years of studies on a variety of skin types and surfaces, we are proud to be hypoallergenic, fragrance-free and 100% non-toxic.